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Steroid Hormone Receptors: Basic and Clinical Aspects

Author : V. K. Moudgil
Publisher : Birkhäuser
Release Date : 2012-11-25
ISBN : 9781461598510
Pages : 0 pages
Rating : 4.5/5 (516 Download)

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Download and Read Steroid Hormone Receptors: Basic and Clinical Aspects PDF by V. K. Moudgil Full Book and published by Birkhäuser. This book was released on 2012-11-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past few years have witnessed the emergence of steroid hormones as the wonder molecules which generate as much discussion in the scientific literature as they do in a typical living room. This transition has been a result of the tremendous public and scientific interest in the normal functioning of the hor mones as well their suggested involvement in several clinical conditions. In the recent past, notable scientific and technological advances have been made in the areas of contraception and regulation of fertility. Steroid receptors are the indis pensable mediators of hormonal responses and are complex protein molecules which appear to exist in association with other, yet undefined, proteins and/or factors. Receptors for vitamin D, retinoic acid and the thyroid hormones share structural similarities with steroid receptors, and the roster of this superfamily is still expanding. While our knowledge of the diversity and magnitude of steroid effects has advanced, the precise mode of steroid hormone action has alluded investigators. This volume brings together an international team of prominent investigators who discuss their most recent work on the basic and clinical aspects of steroid/nuclear receptors. The contributions represent updated versions of the invited presentations made at The Second Meadow Brook Conference on Steroid Receptors in Health and Disease. I am grateful to my colleagues on the Scientific Committee: Etienne Baulieu, Jack Gorski, Benita Katzenellenbogen, David Toft and James WittJiff, who provided the vision and guidance in formulating an out standing program.

Steroid Hormone Receptors

Author : V. K. Moudgil
Publisher :
Release Date : 1994
ISBN : 9783764336943
Pages : pages
Rating : 4.9/5 (943 Download)

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Download and Read Steroid Hormone Receptors PDF by V. K. Moudgil Full Book and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Steroid Hormone Receptors

Author : Virinder K. Moudgil
Publisher : Birkhauser
Release Date : 1994
ISBN :
Pages : 544 pages
Rating : 4.1/5 (15 Download)

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Download and Read Steroid Hormone Receptors PDF by Virinder K. Moudgil Full Book and published by Birkhauser. This book was released on 1994 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: The molecular mechanisms and gene expression pathways are thoroughly covered in this exceptional volume. The reviews are written by the field's top investigators, yet they are easy to read for students and researchers alike. Clinicians will be interested in the chapters which cover the molecular and biological aspects of disease. Molecular and cell biologists, biochemists, endocrinologists, and pharmaceutical researchers will all benefit from this comprehensive volume.

Estrogens, Progestins, and Their Antagonists

Author : Edward J. Pavlik
Publisher : Birkhäuser
Release Date : 2012-11-19
ISBN : 1461220041
Pages : 234 pages
Rating : 4.2/5 (22 Download)

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Download and Read Estrogens, Progestins, and Their Antagonists PDF by Edward J. Pavlik Full Book and published by Birkhäuser. This book was released on 2012-11-19 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: These two volumes on Estrogens, Progestins, and Their Antagonists repre sent a thematic extension of the series, Hormones in Health and Disease. The first publication in the series, Steroid Hormone Receptors: Basic and Clinical Aspects, focused on recent advances in the anatomy of steroid receptors and members of the steroid receptor superfamily. Consistent with the spirit of the series, the authors addressed issues of clinical significance of steroid receptor detection in hormone-related disorders. The second volume in the series, Hormones and Cancer, attempted a more direct examination of ac tions of hormones in cancerous tissues and cells. In these two volumes, which together form the third in the series, the editor, Dr. Edward Pavlik, has introduced a team of leading investigators engaged in research on various aspects of the steroids that regulate female reproductive physiology. Estrogens and progestins, the main components of the most widely used contraceptive pills, have found a variety of uses in clinical endocrinology. These volumes contain discussions that range from the introduction of novel hormonal ligands to "hormonal antagonism by steroid analogs. A balanced treatment is provided of applications of the steroids in treatment and management of hormone-dependent conditions and malignancies. The remarkable synthesis of literature contained in this volume will provide a reader with both the fundamental concepts underly ing steroid hormone physiology and the clinical applications of observations made on basic aspects of hormone action. I congratulate the editorial leadership of Dr.

Steroid Receptors in Health and Disease

Author : Virinder Moudgil
Publisher : Springer
Release Date : 2012-12-27
ISBN : 9781468455434
Pages : 334 pages
Rating : 4.4/5 (435 Download)

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Download and Read Steroid Receptors in Health and Disease PDF by Virinder Moudgil Full Book and published by Springer. This book was released on 2012-12-27 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades, progress in steroid hormone research has resulted in the development of new approaches to contraception as well as diagnosis and treatment of endocrine disorders and cancers. Although significant advances have been made in the purification, characterization, immunochemistry and molecular biology of steroid receptors, the precise molecular mechanism of steroid hormone action has remained obscure. This book captures the detailed presentations made at the first conference on Steroid Receptors in Health and Disease held at Meadow Brook Hall, Oakland University in the fall of 1987. The purpose of this international con ference was to facilitate scientific exchange toward a better understand ing of the mode of action of steroid hormones. The scientific sessions consisted of poster presentations and state-of-the-art lectures, the latter of which make up this volume. The first chapter is meant to provide the reader with a more general background of the topics covered in the book, as well as to discuss certain theme-related issues that are either not yet well-established or accepted or are in the stage of infancy. It is hoped that this volume will serve as a useful treatise for students and investigators interested in basic and clinical aspects of biological regulation by steroid hormones. A task of this magnitude could not have been undertaken without the encouragement, advice and continued generous assistance of the members of the scientific committee. I am gratefully indebted to Drs.

Steroid Hormone Receptors: Basic and Clinical Aspects

Author : V. K. Moudgil
Publisher : Springer Science & Business Media
Release Date : 2013-03-13
ISBN : 1461598494
Pages : 522 pages
Rating : 4.5/5 (598 Download)

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Download and Read Steroid Hormone Receptors: Basic and Clinical Aspects PDF by V. K. Moudgil Full Book and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 522 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past few years have witnessed the emergence of steroid hormones as the wonder molecules which generate as much discussion in the scientific literature as they do in a typical living room. This transition has been a result of the tremendous public and scientific interest in the normal functioning of the hor mones as well their suggested involvement in several clinical conditions. In the recent past, notable scientific and technological advances have been made in the areas of contraception and regulation of fertility. Steroid receptors are the indis pensable mediators of hormonal responses and are complex protein molecules which appear to exist in association with other, yet undefined, proteins and/or factors. Receptors for vitamin D, retinoic acid and the thyroid hormones share structural similarities with steroid receptors, and the roster of this superfamily is still expanding. While our knowledge of the diversity and magnitude of steroid effects has advanced, the precise mode of steroid hormone action has alluded investigators. This volume brings together an international team of prominent investigators who discuss their most recent work on the basic and clinical aspects of steroid/nuclear receptors. The contributions represent updated versions of the invited presentations made at The Second Meadow Brook Conference on Steroid Receptors in Health and Disease. I am grateful to my colleagues on the Scientific Committee: Etienne Baulieu, Jack Gorski, Benita Katzenellenbogen, David Toft and James WittJiff, who provided the vision and guidance in formulating an out standing program.

Estrogens, Progestins and their Antagonists

Author : Edward J. Pavlik
Publisher : Birkhäuser
Release Date : 2013-06-12
ISBN : 9781461274940
Pages : 561 pages
Rating : 4.9/5 (94 Download)

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Download and Read Estrogens, Progestins and their Antagonists PDF by Edward J. Pavlik Full Book and published by Birkhäuser. This book was released on 2013-06-12 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: These two volumes on Estrogens, Progestins, and Their Antagonists repre sent a thematic extension of the series, Hormones in Health and Disease. The first publication in the series, Steroid Hormone Receptors: Basic and Clinical Aspects, focused on recent advances in the anatomy of steroid receptors and members of the steroid receptor superfamily. Consistent with the spirit of the series, the authors addressed issues of clinical significance of steroid receptor detection in hormone-related disorders. The second volume in the series, Hormones and Cancer, attempted a more direct examination of ac tions of hormones in cancerous tissues and cells. In these two volumes, which together form the third in the series, the editor, Dr. Edward Pavlik, has introduced a team of leading investigators engaged in research on various aspects of the steroids that regulate female reproductive physiology. Estrogens and progestins, the main components of the most widely used contraceptive pills, have found a variety of uses in clinical endocrinology. These volumes contain discussions that range from the introduction of novel hormonal ligands to hormonal antagonism by steroid analogs. A balanced treatment is provided of applications of the steroids in treatment and management of hormone-dependent conditions and malignancies. The remarkable synthesis of literature contained in this volume will provide a reader with both the fundamental concepts underly ing steroid hormone physiology and the clinical applications of observations made on basic aspects of hormone action. I congratulate the editorial leadership of Dr.

Estrogens, Progestins, and Their Antagonists

Author : Edward J. Pavlik
Publisher : Birkhäuser
Release Date : 1997-02-01
ISBN : 9780817639471
Pages : 234 pages
Rating : 4.4/5 (47 Download)

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Download and Read Estrogens, Progestins, and Their Antagonists PDF by Edward J. Pavlik Full Book and published by Birkhäuser. This book was released on 1997-02-01 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: These two volumes on Estrogens, Progestins, and Their Antagonists repre sent a thematic extension of the series, Hormones in Health and Disease. The first publication in the series, Steroid Hormone Receptors: Basic and Clinical Aspects, focused on recent advances in the anatomy of steroid receptors and members of the steroid receptor superfamily. Consistent with the spirit of the series, the authors addressed issues of clinical significance of steroid receptor detection in hormone-related disorders. The second volume in the series, Hormones and Cancer, attempted a more direct examination of ac tions of hormones in cancerous tissues and cells. In these two volumes, which together form the third in the series, the editor, Dr. Edward Pavlik, has introduced a team of leading investigators engaged in research on various aspects of the steroids that regulate female reproductive physiology. Estrogens and progestins, the main components of the most widely used contraceptive pills, have found a variety of uses in clinical endocrinology. These volumes contain discussions that range from the introduction of novel hormonal ligands to "hormonal antagonism by steroid analogs. A balanced treatment is provided of applications of the steroids in treatment and management of hormone-dependent conditions and malignancies. The remarkable synthesis of literature contained in this volume will provide a reader with both the fundamental concepts underly ing steroid hormone physiology and the clinical applications of observations made on basic aspects of hormone action. I congratulate the editorial leadership of Dr.

Estrogens, Progestins, and Their Antagonists

Author : Edward J. Pavlik
Publisher : Birkhäuser
Release Date : 1997-02-01
ISBN : 9780817639471
Pages : 234 pages
Rating : 4.4/5 (47 Download)

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Download and Read Estrogens, Progestins, and Their Antagonists PDF by Edward J. Pavlik Full Book and published by Birkhäuser. This book was released on 1997-02-01 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: These two volumes on Estrogens, Progestins, and Their Antagonists repre sent a thematic extension of the series, Hormones in Health and Disease. The first publication in the series, Steroid Hormone Receptors: Basic and Clinical Aspects, focused on recent advances in the anatomy of steroid receptors and members of the steroid receptor superfamily. Consistent with the spirit of the series, the authors addressed issues of clinical significance of steroid receptor detection in hormone-related disorders. The second volume in the series, Hormones and Cancer, attempted a more direct examination of ac tions of hormones in cancerous tissues and cells. In these two volumes, which together form the third in the series, the editor, Dr. Edward Pavlik, has introduced a team of leading investigators engaged in research on various aspects of the steroids that regulate female reproductive physiology. Estrogens and progestins, the main components of the most widely used contraceptive pills, have found a variety of uses in clinical endocrinology. These volumes contain discussions that range from the introduction of novel hormonal ligands to "hormonal antagonism by steroid analogs. A balanced treatment is provided of applications of the steroids in treatment and management of hormone-dependent conditions and malignancies. The remarkable synthesis of literature contained in this volume will provide a reader with both the fundamental concepts underly ing steroid hormone physiology and the clinical applications of observations made on basic aspects of hormone action. I congratulate the editorial leadership of Dr.

Steroid Hormone Resistance

Author : George P. Chrousos
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
ISBN : 1468451014
Pages : 439 pages
Rating : 4.4/5 (451 Download)

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Download and Read Steroid Hormone Resistance PDF by George P. Chrousos Full Book and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents the first attempt to present in one place the clinical syndromes and the pathophysiologic basis for the "resistance states" to each of the classes of steroid hormones. Glucocorticoids, mineralocorticoids, androgens, estrogens, progesterone and vitamin D have widely diverse roles ranging from the control of homeostasis to reproduction and bone formation. They are similar in that they share a chemical structure and that their action is in the cell nucleus where they induce transcription of specific genes leading to synthesis of function-specific proteins. Clinical syndromes of steroid hormone resistance to androgens (complete and partial testicular feminization), aldosterone (pseudo hypoaldosteronism) and vitamin D (vitamin D-dependent rickets type II) have been known for many years. Progesterone and glucocorticoid resistance syndromes have been described only recently. Resistance to estrogens has not been reported in man or in animals. It is hoped that a detailed reexamination of what is known about each of these conditions at the clinical and molecular levels will enhance our understanding of the function of these hormones and their mechanisms of action. New insight and research initiatives should result. G.P. Chrousos D.L. Loriaus M.B. Lipsett vii ACKNOWLEDGMENTS The contents of this volume are based in part on the proceedings of an International Conference held in Bethesda in the summer of 1984. This conference was sponsored by the National Institute of Child Health and Human Development, Bethesda, Maryland.

Estrogens, Progestins and their Antagonists

Author : Edward J. Pavlik
Publisher : Birkhäuser
Release Date : 1997-02-01
ISBN : 9780817639488
Pages : 0 pages
Rating : 4.4/5 (489 Download)

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Download and Read Estrogens, Progestins and their Antagonists PDF by Edward J. Pavlik Full Book and published by Birkhäuser. This book was released on 1997-02-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: These two volumes on Estrogens, Progestins, and Their Antagonists repre sent a thematic extension of the series, Hormones in Health and Disease. The first publication in the series, Steroid Hormone Receptors: Basic and Clinical Aspects, focused on recent advances in the anatomy of steroid receptors and members of the steroid receptor superfamily. Consistent with the spirit of the series, the authors addressed issues of clinical significance of steroid receptor detection in hormone-related disorders. The second volume in the series, Hormones and Cancer, attempted a more direct examination of ac tions of hormones in cancerous tissues and cells. In these two volumes, which together form the third in the series, the editor, Dr. Edward Pavlik, has introduced a team of leading investigators engaged in research on various aspects of the steroids that regulate female reproductive physiology. Estrogens and progestins, the main components of the most widely used contraceptive pills, have found a variety of uses in clinical endocrinology. These volumes contain discussions that range from the introduction of novel hormonal ligands to hormonal antagonism by steroid analogs. A balanced treatment is provided of applications of the steroids in treatment and management of hormone-dependent conditions and malignancies. The remarkable synthesis of literature contained in this volume will provide a reader with both the fundamental concepts underly ing steroid hormone physiology and the clinical applications of observations made on basic aspects of hormone action. I congratulate the editorial leadership of Dr.

Estrogens, Progestins and their Antagonists

Author : Edward J. Pavlik
Publisher : Birkhäuser
Release Date : 2014-09-12
ISBN : 9781461223061
Pages : 0 pages
Rating : 4.0/5 (67 Download)

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Download and Read Estrogens, Progestins and their Antagonists PDF by Edward J. Pavlik Full Book and published by Birkhäuser. This book was released on 2014-09-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: These two volumes on Estrogens, Progestins, and Their Antagonists repre sent a thematic extension of the series, Hormones in Health and Disease. The first publication in the series, Steroid Hormone Receptors: Basic and Clinical Aspects, focused on recent advances in the anatomy of steroid receptors and members of the steroid receptor superfamily. Consistent with the spirit of the series, the authors addressed issues of clinical significance of steroid receptor detection in hormone-related disorders. The second volume in the series, Hormones and Cancer, attempted a more direct examination of ac tions of hormones in cancerous tissues and cells. In these two volumes, which together form the third in the series, the editor, Dr. Edward Pavlik, has introduced a team of leading investigators engaged in research on various aspects of the steroids that regulate female reproductive physiology. Estrogens and progestins, the main components of the most widely used contraceptive pills, have found a variety of uses in clinical endocrinology. These volumes contain discussions that range from the introduction of novel hormonal ligands to hormonal antagonism by steroid analogs. A balanced treatment is provided of applications of the steroids in treatment and management of hormone-dependent conditions and malignancies. The remarkable synthesis of literature contained in this volume will provide a reader with both the fundamental concepts underly ing steroid hormone physiology and the clinical applications of observations made on basic aspects of hormone action. I congratulate the editorial leadership of Dr.

Steroid-protein Interactions

Author : Roberto Frairia
Publisher :
Release Date : 1988
ISBN :
Pages : 344 pages
Rating : 4.D/5 (3 Download)

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Download and Read Steroid-protein Interactions PDF by Roberto Frairia Full Book and published by . This book was released on 1988 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Steroid Receptor Assays in Human Breast Tumours

Author : Roger John Benjamin King
Publisher :
Release Date : 1979
ISBN :
Pages : 120 pages
Rating : 4.9/5 (978 Download)

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Download and Read Steroid Receptor Assays in Human Breast Tumours PDF by Roger John Benjamin King Full Book and published by . This book was released on 1979 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Encyclopedia of Science and Technology

Author : James Trefil
Publisher : Routledge
Release Date : 2001-08-24
ISBN : 113675363X
Pages : 554 pages
Rating : 4.7/5 (753 Download)

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Download and Read The Encyclopedia of Science and Technology PDF by James Trefil Full Book and published by Routledge. This book was released on 2001-08-24 with total page 554 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by acclaimed science writer and physicist James Trefil, the Encyclopedia's 1000 entries combine in-depth coverage with a vivid graphic format to bring every facet of science, technology, and medicine into stunning focus. From absolute zero to the Mesozoic era to semiconductors to the twin paradox, Trefil and his co-authors have an uncanny ability to convey how the universe works and to show readers how to apply that knowledge to everyday problems.

Vitamin D

Author : Michael F. Holick
Publisher : Springer Science & Business Media
Release Date : 2013-03-09
ISBN : 1475728611
Pages : 458 pages
Rating : 4.7/5 (728 Download)

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Download and Read Vitamin D PDF by Michael F. Holick Full Book and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nutrition and Health series of books has as an overriding mission to provide health professionals with texts that are considered essential because each includes: a synthesis of the state of the science; timely, in-depth reviews by the leading researchers in their respective fields; extensive, up-to-date fully annotated reference lists; a detailed index; relevant tables and figures; identification of paradigm shifts and the consequences; of information between chapters, but targeted, inter-chapter refer virtually no overlap rals, suggestions of areas for future research; and balanced, data-driven answers to patient questions that are based on the totality of evidence rather than the findings of any single study. The series volumes are not the outcome of a symposium. Rather, each editor has the potential to examine a chosen area with a broad perspective, both in subject matter as well as in the choice of chapter authors. The international perspective, especially with regard to public health initiatives, is emphasized where appropriate. The editors, whose training is both research and practice oriented, have the opportunity to develop a primary objective for their book, define the scope and focus, and then invite the leading authori ties from around the world to be part of their initiative. The authors are encouraged to provide an overview of the field, discuss their own research, and relate the research de findings to potential human health consequences.

Metamorphosis

Author :
Publisher : Academic Press
Release Date : 1996-02-21
ISBN : 0080536352
Pages : 687 pages
Rating : 4.5/5 (536 Download)

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Download and Read Metamorphosis PDF by Full Book and published by Academic Press. This book was released on 1996-02-21 with total page 687 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metamorphosis addresses various facets of postembryonic development, particularly signal transduction, morphogenesis, cell-cell interactions, and programmed cell death. A key feature of the book is its exploration of the molecular mechanisms underlying these processes. Hormonal regulation of development The mechanisms of hormone action The steroid/thyroid hormone receptor family Morphogenesis and programmed cell death