Download Statistical Genomics PDF

Statistical Genomics

Author :
Publisher : CRC Press
Release Date :
ISBN : 1351414534
Pages : 648 pages
Rating : 4.4/5 (414 Download)

Download Free Statistical Genomics PDF by Ben Hui Liu Full Book and published by CRC Press. This book was released on 2017-11-22 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomics, the mapping of the entire genetic complement of an organism, is the new frontier in biology. This handbook on the statistical issues of genomics covers current methods and the tried-and-true classical approaches.


Download Principles of Statistical Genomics PDF

Principles of Statistical Genomics

Author :
Publisher : Springer Science & Business Media
Release Date :
ISBN : 0387708065
Pages : 428 pages
Rating : 4.7/5 (78 Download)

Download Free Principles of Statistical Genomics PDF by Shizhong Xu Full Book and published by Springer Science & Business Media. This book was released on 2012-09-10 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical genomics is a rapidly developing field, with more and more people involved in this area. However, a lack of synthetic reference books and textbooks in statistical genomics has become a major hurdle on the development of the field. Although many books have been published recently in bioinformatics, most of them emphasize DNA sequence analysis under a deterministic approach. Principles of Statistical Genomics synthesizes the state-of-the-art statistical methodologies (stochastic approaches) applied to genome study. It facilitates understanding of the statistical models and methods behind the major bioinformatics software packages, which will help researchers choose the optimal algorithm to analyze their data and better interpret the results of their analyses. Understanding existing statistical models and algorithms assists researchers to develop improved statistical methods to extract maximum information from their data. Resourceful and easy to use, Principles of Statistical Genomics is a comprehensive reference for researchers and graduate students studying statistical genomics.


Download Handbook of Statistical Genomics PDF

Handbook of Statistical Genomics

Author :
Publisher : John Wiley & Sons
Release Date :
ISBN : 1119429145
Pages : 1224 pages
Rating : 4.4/5 (429 Download)

Download Free Handbook of Statistical Genomics PDF by David J. Balding Full Book and published by John Wiley & Sons. This book was released on 2019-09-16 with total page 1224 pages. Available in PDF, EPUB and Kindle. Book excerpt: A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.


Download Methods in Statistical Genomics PDF

Methods in Statistical Genomics

Author :
Publisher : RTI Press
Release Date :
ISBN : 1934831166
Pages : 163 pages
Rating : 4.8/5 (831 Download)

Download Free Methods in Statistical Genomics PDF by Philip Chester Cooley Full Book and published by RTI Press. This book was released on 2016-08-29 with total page 163 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this book is to describe procedures for analyzing genome-wide association studies (GWAS). Some of the material is unpublished and contains commentary and unpublished research; other chapters (Chapters 4 through 7) have been published in other journals. Each previously published chapter investigates a different genomics model, but all focus on identifying the strengths and limitations of various statistical procedures that have been applied to different GWAS scenarios.


Download Inference for Sparse and Asymmetric Signals in High Dimensional Data with Applications to Statistical Genomics PDF

Inference for Sparse and Asymmetric Signals in High Dimensional Data with Applications to Statistical Genomics

Author :
Publisher :
Release Date :
ISBN :
Pages : 188 pages
Rating : 4.:/5 (31 Download)

Download Free Inference for Sparse and Asymmetric Signals in High Dimensional Data with Applications to Statistical Genomics PDF by Min Zhang Full Book and published by . This book was released on 2005 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: We also developed a Bayesian model selection approach to select significant predictors from high dimensional linear models. Unlike classical approaches, this method incorporates the important information in high dimensional sparse data that, most of the predictors have no effect or the effects are too small to be detectable, and that positive effects and negative effects may not be symmetric. In addition, this Bayesian approach can naturally handle the important case that deals with missing data. The inference was carried out by using a Markov chain Monte Carlo (MCMC) sampling scheme. We evaluate the performance of this approach by simulation studies as well as applications to quantitative trait loci (QTL) mapping. This approach can be applied to both independent and clustered data.


Download Proceedings of the Indian National Science Academy PDF

Proceedings of the Indian National Science Academy

Author :
Publisher :
Release Date :
ISBN :
Pages : pages
Rating : 4.4/5 (469 Download)

Download Free Proceedings of the Indian National Science Academy PDF by Indian National Science Academy Full Book and published by . This book was released on 2001 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Proceedings PDF

Proceedings

Author :
Publisher :
Release Date :
ISBN :
Pages : pages
Rating : 4.6/5 (695 Download)

Download Free Proceedings PDF by Indian National Science Academy Full Book and published by . This book was released on 2003 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Statistical Methods in Molecular Evolution PDF

Statistical Methods in Molecular Evolution

Author :
Publisher : Springer Science & Business Media
Release Date :
ISBN : 9780387223339
Pages : 505 pages
Rating : 4.3/5 (339 Download)

Download Free Statistical Methods in Molecular Evolution PDF by Rasmus Nielsen Full Book and published by Springer Science & Business Media. This book was released on 2005-04-21 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the field of molecular evolution, inferences about past evolutionary events are made using molecular data from currently living species. With the availability of genomic data from multiple related species, molecular evolution has become one of the most active and fastest growing fields of study in genomics and bioinformatics. Most studies in molecular evolution rely heavily on statistical procedures based on stochastic process modelling and advanced computational methods including high-dimensional numerical optimization and Markov Chain Monte Carlo. This book provides an overview of the statistical theory and methods used in studies of molecular evolution. It includes an introductory section suitable for readers that are new to the field, a section discussing practical methods for data analysis, and more specialized sections discussing specific models and addressing statistical issues relating to estimation and model choice. The chapters are written by the leaders of field and they will take the reader from basic introductory material to the state-of-the-art statistical methods. This book is suitable for statisticians seeking to learn more about applications in molecular evolution and molecular evolutionary biologists with an interest in learning more about the theory behind the statistical methods applied in the field. The chapters of the book assume no advanced mathematical skills beyond basic calculus, although familiarity with basic probability theory will help the reader. Most relevant statistical concepts are introduced in the book in the context of their application in molecular evolution, and the book should be accessible for most biology graduate students with an interest in quantitative methods and theory. Rasmus Nielsen received his Ph.D. form the University of California at Berkeley in 1998 and after a postdoc at Harvard University, he assumed a faculty position in Statistical Genomics at Cornell University. He is currently an Ole Rømer Fellow at the University of Copenhagen and holds a Sloan Research Fellowship. His is an associate editor of the Journal of Molecular Evolution and has published more than fifty original papers in peer-reviewed journals on the topic of this book. From the reviews: "...Overall this is a very useful book in an area of increasing importance." Journal of the Royal Statistical Society "I find Statistical Methods in Molecular Evolution very interesting and useful. It delves into problems that were considered very difficult just several years ago...the book is likely to stimulate the interest of statisticians that are unaware of this exciting field of applications. It is my hope that it will also help the 'wet lab' molecular evolutionist to better understand mathematical and statistical methods." Marek Kimmel for the Journal of the American Statistical Association, September 2006 "Who should read this book? We suggest that anyone who deals with molecular data (who does not?) and anyone who asks evolutionary questions (who should not?) ought to consult the relevant chapters in this book." Dan Graur and Dror Berel for Biometrics, September 2006 "Coalescence theory facilitates the merger of population genetics theory with phylogenetic approaches, but still, there are mostly two camps: phylogeneticists and population geneticists. Only a few people are moving freely between them. Rasmus Nielsen is certainly one of these researchers, and his work so far has merged many population genetic and phylogenetic aspects of biological research under the umbrella of molecular evolution. Although Nielsen did not contribute a chapter to his book, his work permeates all its chapters. This book gives an overview of his interests and current achievements in molecular evolution. In short, this book should be on your bookshelf." Peter Beerli for Evolution, 60(2), 2006


Download Cornell University Courses of Study PDF

Cornell University Courses of Study

Author :
Publisher :
Release Date :
ISBN :
Pages : pages
Rating : 4.:/5 (31 Download)

Download Free Cornell University Courses of Study PDF by Cornell University Full Book and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Computational and Statistical Approaches to Genomics PDF

Computational and Statistical Approaches to Genomics

Author :
Publisher : Springer
Release Date :
ISBN : 9780387262871
Pages : 416 pages
Rating : 4.8/5 (873 Download)

Download Free Computational and Statistical Approaches to Genomics PDF by Wei Zhang Full Book and published by Springer. This book was released on 2006-05-04 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this book adds eight new contributors to reflect a modern cutting edge approach to genomics. It contains the newest research results on genomic analysis and modeling using state-of-the-art methods from engineering, statistics, and genomics. These tools and models are then applied to real biological and clinical problems. The book’s original seventeen chapters are also updated to provide new initiatives and directions.


Download AMSTAT News PDF

AMSTAT News

Author :
Publisher :
Release Date :
ISBN :
Pages : pages
Rating : 4.1/5 (15 Download)

Download Free AMSTAT News PDF by American Statistical Association Full Book and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Statistical Population Genomics PDF

Statistical Population Genomics

Author :
Publisher : Humana
Release Date :
ISBN : 9781071602010
Pages : 468 pages
Rating : 4.0/5 (12 Download)

Download Free Statistical Population Genomics PDF by Julien Y. Dutheil Full Book and published by Humana. This book was released on 2020-09-18 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques. After introducing general concepts related to the biology of genomes and their evolution, the book covers state-of-the-art methods for the analysis of genomes in populations, including demography inference, population structure analysis and detection of selection, using both model-based inference and simulation procedures. Last but not least, it offers an overview of the current knowledge acquired by applying such methods to a large variety of eukaryotic organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, pointers to the relevant literature, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Statistical Population Genomics aims to promote and ensure successful applications of population genomic methods to an increasing number of model systems and biological questions.


Download Human Population Genetics and Genomics PDF

Human Population Genetics and Genomics

Author :
Publisher : Academic Press
Release Date :
ISBN : 0123860261
Pages : 498 pages
Rating : 4.8/5 (86 Download)

Download Free Human Population Genetics and Genomics PDF by Alan R. Templeton Full Book and published by Academic Press. This book was released on 2018-11-08 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed. Comprehensively explains the use of population genetics and genomics in medical applications and research Discusses the relevance of population genetics and genomics to major social issues, including race and the dangers of modern eugenics proposals Provides an overview of how population genetics and genomics helps us understand where we came from as a species and how we evolved into who we are now


Download Molecular Evolution PDF

Molecular Evolution

Author :
Publisher : OUP Oxford
Release Date :
ISBN : 0191023310
Pages : 528 pages
Rating : 4.0/5 (23 Download)

Download Free Molecular Evolution PDF by Ziheng Yang Full Book and published by OUP Oxford. This book was released on 2014-05-15 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Studies of evolution at the molecular level have experienced phenomenal growth in the last few decades, due to rapid accumulation of genetic sequence data, improved computer hardware and software, and the development of sophisticated analytical methods. The flood of genomic data has generated an acute need for powerful statistical methods and efficient computational algorithms to enable their effective analysis and interpretation. Molecular Evolution: a statistical approach presents and explains modern statistical methods and computational algorithms for the comparative analysis of genetic sequence data in the fields of molecular evolution, molecular phylogenetics, statistical phylogeography, and comparative genomics. Written by an expert in the field, the book emphasizes conceptual understanding rather than mathematical proofs. The text is enlivened with numerous examples of real data analysis and numerical calculations to illustrate the theory, in addition to the working problems at the end of each chapter. The coverage of maximum likelihood and Bayesian methods are in particular up-to-date, comprehensive, and authoritative. This advanced textbook is aimed at graduate level students and professional researchers (both empiricists and theoreticians) in the fields of bioinformatics and computational biology, statistical genomics, evolutionary biology, molecular systematics, and population genetics. It will also be of relevance and use to a wider audience of applied statisticians, mathematicians, and computer scientists working in computational biology.


Download Statistical Techniques in Life-testing, Reliability, Sampling Theory and Quality Control PDF

Statistical Techniques in Life-testing, Reliability, Sampling Theory and Quality Control

Author :
Publisher : Narosa Publishing House
Release Date :
ISBN :
Pages : 215 pages
Rating : 4.0/5 (1 Download)

Download Free Statistical Techniques in Life-testing, Reliability, Sampling Theory and Quality Control PDF by B. N. Pandey Full Book and published by Narosa Publishing House. This book was released on 2007 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Statistical Techniques in Life-Testing, Reliability, Sampling Theory and Quality Control covers recent research in the unified branches of theoretical and applied Statistics on common platform. These generally involve the concept of probability theory, prior information (Bayes and Minimax both), distribution theory, order statistics censoring, Truncation, loss and risk function, conditional distribution (sufficiency and complete sufficiency), sampling techniques using non-response techniques and Post- Stratification etc. Log-normal models in survival data, Bernoulli's trials, regression, ration under non necessarily model, CUSUM techniques in control charts, and reliability models with wide applications in other disciplines such as biology, mining and coal, industries, agriculture population, science and technology, medical sciences, research organizations, engineering, operation research, cancer institute, defense organizations, etc. are also discussed.


Download Calcutta Statistical Association Bulletin PDF

Calcutta Statistical Association Bulletin

Author :
Publisher :
Release Date :
ISBN :
Pages : pages
Rating : 4.1/5 (15 Download)

Download Free Calcutta Statistical Association Bulletin PDF by Calcutta Statistical Association Full Book and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:


Download Bulletin de L'Institut International de Statistique PDF

Bulletin de L'Institut International de Statistique

Author :
Publisher :
Release Date :
ISBN :
Pages : pages
Rating : 4.D/5 (3 Download)

Download Free Bulletin de L'Institut International de Statistique PDF by International Statistical Institute Full Book and published by . This book was released on 1886 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: V. 1-5, v. 7-10 include "Bulletin bibliographique."